> For the complete documentation index, see [llms.txt](https://kam-1.gitbook.io/kam-docs/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://kam-1.gitbook.io/kam-docs/pharmacy/03_fluids.md).

# Fluids & Blood Compatibility

***

Administering fluids is essential for restoring lost volume, but different fluids have distinct physiological impacts on **Kidney Function (Acidosis)** and **Coagulation (Clotting Factors)**.

## 🩺 Fluid Properties & Effects

When a fluid bag is successfully administered, it updates the patient's acidosis index (internally `externalPh`, where `0` is ideal and `3000` is critical failure) and adds coagulation factors to their clotting pool.

| Fluid Type          | Bag Size |   Acidosis Index Change  | Coagulation Factors Added |
| ------------------- | :------: | :----------------------: | :-----------------------: |
| **Saline**          |  1000ml  |  +750 (worsens acidosis) |             +0            |
|                     |   500ml  |  +350 (worsens acidosis) |             +0            |
|                     |   250ml  |  +150 (worsens acidosis) |             +0            |
| **Plasma**          |  1000ml  | -500 (improves acidosis) |            +20            |
|                     |   500ml  | -250 (improves acidosis) |            +10            |
|                     |   250ml  | -100 (improves acidosis) |             +5            |
| **Blood (Generic)** |  1000ml  | -800 (improves acidosis) |            +16            |
|                     |   500ml  | -400 (improves acidosis) |             +8            |
|                     |   250ml  | -200 (improves acidosis) |             +4            |
| **Blood (Typed)**   |  1000ml  | -800 (improves acidosis) |            +12            |
|                     |   500ml  | -400 (improves acidosis) |             +8            |
|                     |   250ml  | -200 (improves acidosis) |             +4            |

*Note: For more information about the acidosis index, see* [*Kidney Function*](/kam-docs/pharmacy/01_kidneys.md)*.*

***

## 🩸 Blood Group Compatibility

Transfusing typed blood requires ensuring compatibility between the donor blood bag and the recipient patient.

### Rh Factor Rules

* **Rh Negative (-)** blood can be given to **both Rh Negative (-) and Rh Positive (+)** recipients of compatible types.
* **Rh Positive (+)** blood can **only** be given to **Rh Positive (+)** recipients.

### Compatibility Matrix

| Recipient Type | Compatible Blood Types                             |
| -------------- | -------------------------------------------------- |
| **O-**         | O-                                                 |
| **O+**         | O-, O+                                             |
| **A-**         | O-, A-                                             |
| **A+**         | O-, O+, A-, A+                                     |
| **B-**         | O-, B-                                             |
| **B+**         | O-, O+, B-, B+                                     |
| **AB-**        | O-, A-, B-, AB-                                    |
| **AB+**        | *Universal Recipient* (All blood types compatible) |

* **Universal Donor:** **O-** blood can be safely transfused to any recipient type.
* **Universal Recipient:** Patients with **AB+** blood can receive any blood type.

***

## ⚠️ Blood Poisoning

Transfusing an incompatible blood type triggers a severe physiological reaction.

* **Onset:** An incompatible transfusion immediately inflicts the **"BloodPoisoning"** condition in the patient's system.
* **Consequence:** If the poisoning is not resolved, the patient will suffer **immediate Cardiac Arrest after 150 seconds (2.5 minutes)**.
* **Treatment:** To cure blood poisoning, administer a **CWMP (Combat Wound Medication Pack)**. This will safely remove the poisoning condition from the patient's system.